Okay, I don't know for sure what a reprobabte mind is but let's just look at some scriptures that talk about it. Here is the main one I know of, and I found some supporting scrpitures.
Romans 1:18
For the invisible things of him from the creation of the world are clearly seen, being understood by the things that are made, even his eternal power and Godhead; so that they are without excuse: Because that, when they knew God, they glorified him not as God, neither were thankful; but because vain in their imaginations, and their foolish heart was darkened. Professing themselves to be wise, they became fools, and changed the glory of the incorruptible God into an image made like to corruptible man, and to birds, and four footed beasts, and creeping things.
Wherefore God also gave them up to unclenness through the lusts of their own hearts, to dishonour their own bodies between themselves: Who changed the truth of God into a lie, and worshipped and served the creature, (Satan) more than the Creator, (God) who is blessed for ever. A-men. For this cause God gave them up unto vile affections: for even their women did change the natural use into that is against nature: And likewise also the men, leaving the natural use of the woman, burned in their lust one toward another; men with men working that which is unseemly, and receiving in themselves that recompence of their error which was meet.
And even as they did not like to retain God in their knowledge, God gave them over to a reprobate mind, to do those things which are not convenient; Being filled with all unrighteousness, fornication, wickedness, covetousness, maliciousness; full of envy, murder, debaie, deceit, malignity; whispers, Backbiters, haters of God, despiteful, proud, boasters inventors of evil things, disobedient to parents, Without understnding, covenant breakers, without natural affection, implacable, unmerciful: Who knowing the judgment such things are worthy of death, not only do the same, but have pleasure in them that do them.
I know there are more examples in the end but the two the church likes to harp on and everyone understands is fornication and homosexuality. There are some homosexuals and fornicators who wholeheartedly believe that they are alright but truly they are in the hands of an angry God. God has given them over to a reprobabte mind. If you still feel guilty over sin, I don't think your mind is reprobate.