I agree with Sugarland as well. My commute to work in around 20-30 minutes, but coming home is about double that. Traffic is pretty bad during the evening rush hour (stop and go), but going home 288 toward Pearland is much worse imo (stand still).
Besides rush hour, it is around 20 minutes (give or take) to get from Sugarland to the Galleria area. It's pretty much a straight shot up 59.