I think it is true. Kind of like taking Calcium without Vitamin D. Biotin works best when in balance with other B vitamins. For best results, I would take a B Complex or Super B Complex.
Taking Biotin alone broke me out bad! But now that I take a Super B Complex as well, my skin has stayed clear despite me doubling my Biotin dosage.
I dont think MSM qualifies as a B vitamin, but I could be wrong...
hope this helps!