I don't know what the "Best Brand" of MSM but I started taking Triflex by GNC as a dietary supplement, then I found out from this board that it has positive effects on hair. I didn't know what to attribute my hair growth to. I am now 14 weeks into new growth and I'm not even thinking about a re-touch. I have never been able to go past 8 weeks without a re-touch, my hair would break and be uncontrollable. My new growth is so soft, shiny and manageable. I take 3 tablets a day with meals. Maybe check with a pharmacist to see what brand would work best for you.