Be careful of MSM...Just saw this news flash

lana

Well-Known Member
You may have seen ads for a supplement claiming to treat allergies and many other ailments variously called methyl sulfonyl methane (MSM), crystalline DMSO, DMSO2, and "Vibrant Life." But do the claims fit the reality?

MSM is derived from the liquid solvent dimethyl sulfoxide (DMSO), which was a popular alternative remedy for rheumatoid arthritis and other inflammatory conditions in the 1960s and 1970s. Bathing sore joints in DMSO seemed to reduce arthritic symptoms, and there is some clinical evidence for this benefit.

Both DMSO and MSM appear to be well tolerated and have few noticeable side effects. But recent evidence suggests that they may have significant toxic effects in some cells. One report, for example, showed that MSM induced abnormalities in chromosomes and toxic damage to the gametes (egg and sperm cells) of worms.

There is no clinical evidence that MSM benefits patients with asthma or allergic diseases, and this compound may in fact be unexpectedly toxic. On these grounds, there is good reason to avoid experimenting with MSM, even though it's widely available on the Web and in alternative medicine stores. For more information on DMSO, visit the Web site of the Canadian Health Service.
 
I don't take MSM anymore but I did a few years ago and it interrupted my cycle so I stopped taking it. I know a lot of ladies have seen great benefits from taking it, but we should be careful with anything that we put into our bodies.
 
Lana you beat me to it! As soon as I saw this article I rushed over to post it...lol. I have had awesome results with changes in hair texture and growth using MSM...but this make me a little wary of it....I think I'm off to do more research and I'll let you all know what I find
 
Wow, this makes me kind of nervous. I take about 1/2 teaspoon everyday and have been taking MSM for a little over a year. I haven't experienced the interruption in my cycles though.

Thanks so much for sharing!!! You are right we do have to be very careful of what we put in our bodies.
 
Yeah, I'm not against MSM...but I think we should just be careful. I know some ladies have awesome results and enjoy the change in hair texture, growth or whatever. It interrupted my bc's and just started my cycle up like Hello!

I figured then that it was a no-no for me.
 
I luv Msm...I've been taking it for about 5 months now. The first 2 months my cycle came a week early. After those 2 months, my cycle was back on schedule..:)
 
LawyerBarbie07 said:
Lana you beat me to it! As soon as I saw this article I rushed over to post it...lol. I have had awesome results with changes in hair texture and growth using MSM...but this make me a little wary of it....I think I'm off to do more research and I'll let you all know what I find

Please let us know what you find. I take a very low dosage.
 
Oh no! The Mutli's i take have MSM in them. I'm afraid...because I haven't been getting my cycles regularly(like every other month)....THEY GOTTA GO!
 
Oh lawd... :( I just started taking MSM/Glucosamine complex about a week ago. Hoping I wont have ne adverse effects but if I do, Ill bejust fine w/ letting it go.

Thanks so much for the article!
 
I didn't want anyone to think I was bashing MSM, since so many ladies have had good results. I know for me it just messed up my cycle and I am tooo scary to have that happen. I never used it for allergies. I also thought it was derived from shellfish but the article doesn't mention that...?
 
lana said:
I didn't want anyone to think I was bashing MSM, since so many ladies have had good results. I know for me it just messed up my cycle and I am tooo scary to have that happen. I never used it for allergies. I also thought it was derived from shellfish but the article doesn't mention that...?

Thank you for sharing this! I now know whats going on with me, i will make an appointment though to make confirmation. But when i think about the timelines it all goes together with when i started taken MSM.
 
Having been in the Pharma industry I always question where these reports were done and for whom. It is customary to to testing on pharmaceuticals/ neutraceuticals on animals; pigs, mice, monkeys, birds ascomparable control groups since they have similar structures (nervous system, skeletal, endocrine, etc). I'm sorry but, testing on WORMS in no way would be a comparative test. They are not similar to humans, not even reproductive wise, no nervous system, no skeletal system. This test would be like me saying "salt removes moisture from a slugs body if poured directly on it causing death so therefore it must do the same for humans :confused:" . That conclusion would be just as credible as the one in that article. I'm surprised someone could be that wreckless and irresponsible in actually publishing those kind of findings and suggesting it would conversely apply to humans. WTF.
 
tnorenberg said:
Having been in the Pharma industry I always question where these reports were done and for whom. It is customary to to testing on pharmaceuticals/ neutraceuticals on animals; pigs, mice, monkeys, birds ascomparable control groups since they have similar structures (nervous system, skeletal, endocrine, etc). I'm sorry but, testing on WORMS in no way would be a comparative test. They are not similar to humans, not even reproductive wise, no nervous system, no skeletal system. This test would be like me saying "salt removes moisture from a slugs body if poured directly on it causing death so therefore it must do the same for humans :confused:" . That conclusion would be just as credible as the one in that article. I'm surprised someone could be that wreckless and irresponsible in actually publishing those kind of findings and suggesting it would conversely apply to humans. WTF.
:lachen: Lay that knowledge on us sista! I'm being serious, but what you said about slugs was funny. I guess that's how ridiculous the story was? :perplexed
 
Smells like BS to me. MSM is naturally occuring in food and is in no way toxic at all. At times i have taken 10,000mg of the stuff with no negative side effects. I wonder who funded this "study". Complete BS.
 
tnorenberg said:
Having been in the Pharma industry I always question where these reports were done and for whom. It is customary to to testing on pharmaceuticals/ neutraceuticals on animals; pigs, mice, monkeys, birds ascomparable control groups since they have similar structures (nervous system, skeletal, endocrine, etc). I'm sorry but, testing on WORMS in no way would be a comparative test. They are not similar to humans, not even reproductive wise, no nervous system, no skeletal system. This test would be like me saying "salt removes moisture from a slugs body if poured directly on it causing death so therefore it must do the same for humans :confused:" . That conclusion would be just as credible as the one in that article. I'm surprised someone could be that wreckless and irresponsible in actually publishing those kind of findings and suggesting it would conversely apply to humans. WTF.


Good point.:lachen:
 
I got the story off of Yahoo news if anyone wants to see the source. For the sake of the ladies that take MSM....I hope it's not toxic.

But hey people are going to do what they are going to do. I don't benefit from you guys who take it or don't take it. I just hope everybody does what is best for them. That's all.
 
Wow how ironic! I just bought a bottle of MSM 5 mins ago. I've been hearing ladies rave about MSM for months. Soon as I got home I did a search on LHCF for MSM....and I hear this :perplexed Ah well thanks for the heads up. :scratchch
 
tnorenberg said:
Having been in the Pharma industry I always question where these reports were done and for whom. It is customary to to testing on pharmaceuticals/ neutraceuticals on animals; pigs, mice, monkeys, birds ascomparable control groups since they have similar structures (nervous system, skeletal, endocrine, etc). I'm sorry but, testing on WORMS in no way would be a comparative test. They are not similar to humans, not even reproductive wise, no nervous system, no skeletal system. This test would be like me saying "salt removes moisture from a slugs body if poured directly on it causing death so therefore it must do the same for humans :confused:" . That conclusion would be just as credible as the one in that article. I'm surprised someone could be that wreckless and irresponsible in actually publishing those kind of findings and suggesting it would conversely apply to humans. WTF.


LOL! That's the first thing I thought about too; worms? They have got to be kidding.

Thanks for the info.
 
lana said:
I got the story off of Yahoo news if anyone wants to see the source. For the sake of the ladies that take MSM....I hope it's not toxic.

But hey people are going to do what they are going to do. I don't benefit from you guys who take it or don't take it. I just hope everybody does what is best for them. That's all.
Thank you for thinking of our health darling, much appreciated. Can you show us the yahoo link?

Please dont be offended, ok? :kiss:
 
I took MSM for a year back in 2004. I took it for my joints because they are a hot mess. I never noticed anything strange with the MSM just a little less squeaking and pain in that right ankle of mine.
 
tnorenberg said:
Having been in the Pharma industry I always question where these reports were done and for whom.It is customary to to testing on pharmaceuticals/ neutraceuticals on animals; pigs, mice, monkeys, birds ascomparable control groups since they have similar structures (nervous system, skeletal, endocrine, etc). I'm sorry but, testing on WORMS in no way would be a comparative test. They are not similar to humans, not even reproductive wise, no nervous system, no skeletal system. This test would be like me saying "salt removes moisture from a slugs body if poured directly on it causing death so therefore it must do the same for humans :confused:" . That conclusion would be just as credible as the one in that article. I'm surprised someone could be that wreckless and irresponsible in actually publishing those kind of findings and suggesting it would conversely apply to humans. WTF.

I was thinking the same thing when i read that article. :ohwell:
 
I agree the report seems shady but good looking out for posting. Call me a conspiracy theorist but they just seem to make blanket statements with no supporting evidence. Fat Soluble vitamins can be toxic too...and why don't they state an amount. I bet the Pharma industry is behind it...they don't want anything that they can't force you to get a prescription for.
 
lana said:
You may have seen ads for a supplement claiming to treat allergies and many other ailments variously called methyl sulfonyl methane (MSM), crystalline DMSO, DMSO2, and "Vibrant Life." But do the claims fit the reality?

MSM is derived from the liquid solvent dimethyl sulfoxide (DMSO), which was a popular alternative remedy for rheumatoid arthritis and other inflammatory conditions in the 1960s and 1970s. Bathing sore joints in DMSO seemed to reduce arthritic symptoms, and there is some clinical evidence for this benefit.

Both DMSO and MSM appear to be well tolerated and have few noticeable side effects. But recent evidence suggests that they may have significant toxic effects in some cells. One report, for example, showed that MSM induced abnormalities in chromosomes and toxic damage to the gametes (egg and sperm cells) of worms.

There is no clinical evidence that MSM benefits patients with asthma or allergic diseases, and this compound may in fact be unexpectedly toxic. On these grounds, there is good reason to avoid experimenting with MSM, even though it's widely available on the Web and in alternative medicine stores. For more information on DMSO, visit the Web site of the Canadian Health Service.

I'm not convinced of this statement. Part of my job entails using DMSO to increase viability of cells. Although to much of good thing can be bad for you in general.
 
MSM is found in plants and occurs in a lot of the foods we eat. The only reason we need supplements of it is because it gets destroyed/lost in food preparation, if I'm not mistaken. Anyway, the controversies about it are addressed on the www.dmso.org including the toxicity issue and the conclusion is:
A very extensive toxicology study of DMSO was conducted at 3 to 30 times the usual treatment dose in humans, for 3 months. DMSO appears to be a very safe drug for human administration, and in particular, the lens changes that occur in certain mammalian species do not occur in man under this very high prolonged treatment regimen. I am very glad to be able to present these data at this time, so that we can permanently dispel the myth that DMSO is in any way a toxic or dangerous drug. After considerable work in evaluating thousands of cases that were treated in 1964 and 1965, and after this special toxicology study, I feel that we can unequivocally say that DMSO is quite safe, and now the only necessary task is the proof of its efficacy in specific indications.
 
Thanks Lana!!!!!!! Good looking out!


Kyla





lana said:
You may have seen ads for a supplement claiming to treat allergies and many other ailments variously called methyl sulfonyl methane (MSM), crystalline DMSO, DMSO2, and "Vibrant Life." But do the claims fit the reality?

MSM is derived from the liquid solvent dimethyl sulfoxide (DMSO), which was a popular alternative remedy for rheumatoid arthritis and other inflammatory conditions in the 1960s and 1970s. Bathing sore joints in DMSO seemed to reduce arthritic symptoms, and there is some clinical evidence for this benefit.

Both DMSO and MSM appear to be well tolerated and have few noticeable side effects. But recent evidence suggests that they may have significant toxic effects in some cells. One report, for example, showed that MSM induced abnormalities in chromosomes and toxic damage to the gametes (egg and sperm cells) of worms.

There is no clinical evidence that MSM benefits patients with asthma or allergic diseases, and this compound may in fact be unexpectedly toxic. On these grounds, there is good reason to avoid experimenting with MSM, even though it's widely available on the Web and in alternative medicine stores. For more information on DMSO, visit the Web site of the Canadian Health Service.
 
tnorenberg said:
Having been in the Pharma industry I always question where these reports were done and for whom. It is customary to to testing on pharmaceuticals/ neutraceuticals on animals; pigs, mice, monkeys, birds ascomparable control groups since they have similar structures (nervous system, skeletal, endocrine, etc). I'm sorry but, testing on WORMS in no way would be a comparative test. They are not similar to humans, not even reproductive wise, no nervous system, no skeletal system. This test would be like me saying "salt removes moisture from a slugs body if poured directly on it causing death so therefore it must do the same for humans :confused:" . That conclusion would be just as credible as the one in that article. I'm surprised someone could be that wreckless and irresponsible in actually publishing those kind of findings and suggesting it would conversely apply to humans. WTF.

I'm glad you stepped in with this. My reaction was the same....studies on WORMS??? :confused:

I wouldn't be surprised to find this "study" was sponsored by one of the BIG pharmaceutical companies. The one that profits from Claritin perhaps...

The funny thing is that the article actually makes MSM sound more positive than negative. At the worst your pet worms will have cellular changes or you'll have wasted your money if it doesn't benefit your allergies.



p1

eta: to the OP, we've no qualms with you for posting. thx :)
 
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id like to know at what dosage it may be toxic. it could be a thing where as long at it isnt taken in excess u might be fine? ( hoping so anyway..)

for those doing research..please let us know if u find anything on it...ill will repost too if i find information on it as well!! :)

Thanks OP for the heads up!
 
I don't think any toxicity has been found in humans, at least according to the websites below. With it being water soluble, I'd assume just like Vitamin C, the excess would be flushed out of the body when you pee.

Side Effects:
MSM is considered very safe. Toxicity is extremely rare. No toxic effects were shown in humans given up to one gram per kilogram of body weight (70 Grams or more) per day for 30 days. MSM is generally non-allergenic.
(http://www.falconblanco.com/health/msm/msm.html)

MSM Safety

In long-term toxicity trials with laboratory animals, no toxic MSM effects were found with oral doses of 8 grams MSM per kilogram (2.2 pounds) of body weight. This non-toxic MSM dosage is comparable to 400 grams daily MSM for a 110-pound person. Most people take from 2 to 8 grams total as a daily supplement.

A standard test, known as LD-50 was used to determine the Lethal Dose of MSM. The LD-50 test means Lethal Dose for 50% of the subjects in the test. For MSM, the LD-50 was 20 grams per kilogram of body weight. For perspective, the LD-50 of table salt is 2.5 to 3 grams per kilogram of body weight. MSM thus rates as one of the least toxic substances in biology and medicine. It compares to water, which has an LD-50 rating also greater than 20 grams per kilogram of weight. This is equivalent to taking 2.2 pounds per day for a 110 pound person. Imagine eating 2.2 pounds of anything every day.

Follow-up experiments with human volunteers, found no MSM toxic effects at intake levels of up to 1 gram MSM per kilogram of body weight per day for 30 days. That is equivalent to about 68 grams MSM daily for an average 150-pound person.

MSM presence in the human body was first reported during the 1960s, when a laboratory analysis of the urine of men, women and children found that 4 to 11 milligrams of MSM was excreted over a 24-hour period. In the late 1980s, W. Martin, a researcher at Pharmakin Gmbh, a major German pharmaceutical company, found that MSM is present in human blood plasma. He found about 4 milligrams of MSM in the plasma of an average-size adult.
(http://arthritis-msm-supplement.discount-vitamins-herbs.net/msm-safety.htm)

Side-Effects
MSM is rated as one of the least toxic substances in biology, similar in toxicity to water and much less toxic than common table salt, for example. It has been widely tested as a food ingredient without any reports of allergic reactions.
(http://www.diagnose-me.com/treat/T31893.html)

So MSM is neither a medicine nor a drug, it is a dietary element found naturally in many foods. It should never be confused with the inorganic sulfur compounds used to preserve foods, or the sulfa drugs, which can cause allergic reactions in some people. In fact, acute, intermediate and long term studies indicate that MSM exhibits very low toxicity, even at relatively high dosages. How low? About eight times less toxic than table salt, MSM's toxicity profile is similar to that of glycerine and water! Amazingly, experts find MSM among the safest supplements available. It is even reported to help reduce the body's allergic reaction to many normal allergens.
(http://www.betterhealthsupplies.com/msm.html)
 
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