Once a week, I take my twists down, and finger comb through my hair well, to get rid of the biggest knots/tangles. Then, I soak my hair in conditioner, and let it sit for at least an hour or so. Then, I break my hair into 3-5 sections, and starting from tip to root, I first comb through with my wide toothed comb, then with my medium toothed comb, then with my Denman. After I do that, I twist each section up and pin in down.
When I rinse, I take my denman into the shower, and I brush through each section as I rinse it.
I get out the shower, with my sections still in twists, and let them mostly dry. Then, I take them down, oil with castor oil, comb through with the medium tooth comb, and braid them up to airdry.
When I'm ready to do my twists, I comb through each section (after dousing it in leave-in moisturizer) with a rattail comb, to insure it's totally detangled.
A week later, I repeat it all over again. And even with all that, sometimes I still have velcro ends - it's a sign that I either need an acid rinse, a salt treatment, a clarifying treatment, or a trim. So far (it's been 18 months) I've never gotten to the point of actually trimming.