Hi, this is some info I got of an another board. It's very usefull. MSM DOES cause detox symptoms but that's a good sign, it means your body is getting rid of all its toxins. You could lower your dosage and slowly build it up.
Well here it goes:
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Just in case you're not aware of this, apparently we should be taking half as much vitamin C as we take MSM, for optimal effects. I just read about it in an article by a Naturopathic Physician.
Below I'll copy an excerpt from Benefits of MSM by Dr. Marcy Foley. (You might want to read the rest of the article -- it's encouraging about hair growth!)
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How to take MSM
I have discovered three common mistakes people make when they take MSM, which is why some don't feel it is effective. They don't take enough of it, they don't take it frequently enough or they don't use it with Vitamin C.
It is recommended that a person take 500 mg. MSM for every 30 pounds of body weight. Using a 500 mg. capsule, a 150 pound person could take five capsules, or 2500 mg.
MSM is used up in approximately 12 hours. Therefore, you need to take it twice a day. So the 150 pound person would take five capsules twice a day.
Third, it is suggested that half as much Vitamin C as the amount of MSM be consumed to make the MSM utilizable. In the above example, that means 1250 mg. of Vitamin C.
Those figures are simply a starting place for general health and well being. In cases of severe sulfur deficiency a person may need to take 3-4 times the recommended starting dose mentioned above.
Some people prefer to mix the crystallized or powdered form of MSM in fluid (water or juice), as they feel this gives them better absorption. It does have a somewhat bitter taste and takes quite a bit of stirring to get it to dissolve. One level kitchen teaspoon holds about 4000 mg. of MSM. You can heat the mixing water or juice slightly so that the MSM will dissolve better, and this does not damage the MSM.
As with any supplement, it is best to start at a smaller dose and work up to a higher dose, if you need it. Just don't give up before you get the relief or support you are looking for. Remember that as you are taking higher amounts of MSM, with the concurrent Vitamin C required to assimilate the MSM, you could get diarrhea from either the MSM or the Vitamin C, or both. Therefore, in order to allow your body to absorb the MSM and Vitamin C, you may consider taking this supplement 3-4 times a day instead of twice a day.
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here is the link to the whole article :
Benefits of MSM by Dr. Marcy Foley